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Step Two
This "Hands On" lab experiment is titled, "Histology" Here you'll learn the proper techniques in viewing a tissue slide.
Please go to the following links to get all the instructions for doing your experiments.
EXPERIMENT ONE:
Practice Learning Histology
Purpose:
To develop skills in pattern recognition and identification that will enable the student to be successful at recognizing and correctly identifying human body tissues.
Task:
For a viewing circle with your thumb and fingers. (I’m not kidding!)
This is your pretend microscope ocular lens and field of view of a fabric swatch on your computer screen. Select the first fabric swatch from the link below. Take your finger-thumb ocular and zoom it onto the swatch. Center the round "Field of View" onto the swatch and provide a detailed drawing and a written description on the "Drawings and Description Form" that you can print from the download link provided below. Your written description should describe the shape, size, patterns, color and include as much detailed information about it. Continue until all six fabric swatches have been done. This would be comparable to viewing six different histology slides independently.
Drawings and Description Form: Print from download links below.
Download & Print:
Next select the “All Swatches” link. Can you determine “who’s who” by your drawings and/or descriptions? (Yes or No)*
Which is more useful to you?
Drawing ___
Description ___
Combination of the two ___
Which two fabric swatches are most alike and how are you able to distinguish them?
* If your answer is “No”, redo your drawings looking at the swatches simultaneously. This would be comparable to comparing two or more tissues using separate microscopes set-up side-by-side.
EXPERIMENT TWO:
In this experiment you will use a virtual microscope Tissue Slide Box below to view tissues and skin. This is the exact same tissue box that the on campus students use in lab.
Tissue Slide Box: Move your mouse over any of the slides listed on the black tissue slide box below to view. Click on the slide you wish to view.
When viewing the slides, please follow these steps:
- Start on the lowest magnification 40x
- Move to the next higher magnification 100x
- View the tissue at 400x (Make your sketch of the tissue at this mag.)
- Can you identify any of the cell structures
- Select the Labels "On" button
- Use the slider bars on the side and bottom to scan around the slide.
- View the tissue at 1000x to see the fine ultra structure
Note: Browser Pop-up Blockers must be turn off to view these slides.

Click on any of the slides listed above on the tissue slide box image to view.
Be sure to view, sketch, describe and study the following Tissues:
- Epithelial Tissues
- Simple Squamous Epithelium
- Simple Cuboidal Epithelium
- Simple Columnar Epithelium
- Stratified Squamous Epithelium
- Pseudostratified Columnar Epithelium
- Connective Tissues
- Adipose Tissue
- Hyaline Cartilage
- Dense Regular Connective Tissue
- Bone
- Blood
- Skeletal Muscle
- Cardiac Muscle
- Smooth Muscle
- Nervous Tissue
- Skin
Please don't say, "Boy, all these tissues look alike!". You really need to LOOK hard and try to see patterns, layers, free surfaces, lumens (openings), cell shapes, cell types, striations, etc. These are all clues that help you make the identification of the tissue.
Download the following form and make a sketch and written description of each of the above tissues just like you did with the fabric swatches in Experiment 1. Be sure to note the magnification, location found in the body and the function of the tissue.
Drawings and Description Form: Print from download links below.
Download & Print:
Integumentary System = Skin
The skin images below can be enlarged by moving your mouse cursor over the "Zoom In" link and can be reduced in size by moving the cursor over the "Zoom Out" links. Putting the cursor over the "Normal" link returns the image back to the original image size. These digital images were taken from the same skin model in lab.
Skin Model without labels:
Zoom In | Normal | Zoom Out
Skin Model with labels:
Zoom In | Normal | Zoom Out | Answer Key
Contact me about this lab
| When you have completed the Activity you are ready to move onto the next secton, Assignment. |
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